The Groningen Museum is located opposite the main central station and is the most high-profile museum in the Netherlands. This is due not only to its striking design by Italian architect Mendini, but also because of varying exhibitions, including works by Russian painter Repin, American photographer Andres Serrano, and Dutch photographer Erwin Olaf. The permanent collection consists of a large assembly of porcelain and works by the Groningen artists’ collective De Ploeg.

The Nederlands Stripmuseum is the newest museum in Groningen, and the only one in the Netherlands that highlights comic strips. See comic strip heroes such as Suske en Wiske, Jan, Jans en de kinderen, Dirkjan, and many more. The museum has been divided into special halls for children, adults, and connoisseurs. In addition to an extensive collection of old and new comic strips, there are regular changing exhibitions. See how comic strips are produced; sometimes, you can see a strip cartoonist at work.

The Noordelijk Scheepvaartmuseum ( Nautic Museum) shows the history of trade across Groningen waters. The Niemeyer Tabaksmuseum (Tobacco Museum) has an exhibition of pipes and other objects related to the use of tobacco in the past.

The Grafisch Museum provides an overview of the history of the art of printing, from the earliest methods to modern-day, with regular changing art exhibitions.

The Natuurmuseum focuses particularly on families and children, and provides information about nature and landscape, and the role of human beings in it. There are varying exhibitions, family programmes, and other activities.